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Zuckerman J, de Buck van Overstraeten A, Melmed GY, et al. Improvement in Functional Outcomes Following Ileal Pouch-Anal Anastomosis: Results from the United States Ileal Pouch-Anal Anastomosis Study. Dis Colon Rectum. 2025 Jul 23. doi: 10.1097/DCR.0000000000003894. Epub ahead of print. PMID: 40698674.

This is a prospective study of outcomes of patients undergoing ileal pouch-anal anastomosis for ulcerative colitis or unclassified inflammatory bowel disease. Patient-reported outcomes were assessed preoperatively and at 3, 6, and 12 months using the Colorectal Functional Outcome and Wexner Score for bowel function, International Prostate Symptom Score for urinary function, and PROMIS Sexual Function and Satisfaction and PROMIS Global-10. Sexual interest significantly increased for both men and women, and sexual satisfaction and orgasm ability significantly increased for men. Global physical and mental health also improved. Refer to the article for non-PROMIS-related outcome results.

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Fakorede S, McCloskey C, Wernimont C, Kratz AL, Abou L. Beyond physical function: the impact of nonmotor symptoms on activities and participation in wheelchair users with multiple sclerosis. Int J Rehabil Res. 2025 Jul 17. doi: 10.1097/MRR.0000000000000678. Epub ahead of print. PMID: 40671671.

In this national survey of 89 adult wheelchair users with multiple sclerosis, the authors examined the role of nonmotor symptoms (Fatigue Severity Scale, PROMIS Depression, PROMIS Pain Interference) beyond physical function (PROMIS Physical Function) on activity and participation outcomes. Outcomes included self-efficacy (PROMIS Self-Efficacy for Managing Daily Activities), participation (Community Participation Indicators - control subscale, PROMIS Ability to Participate in Social Roles and Activities), and satisfaction with participation (PROMIS Satisfaction with Social Roles and Activities). Nonmotor symptoms explained 6% additional variance for self-efficacy, 21% additional variance for community participation control, 29% additional variance for social role participation, and 13% additional variance for participation satisfaction. Specifically, pain interference was the nonmotor symptom that was significantly associated with all the outcomes.

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Wolff AC, Absolom K, Ahmed S, et al. Enhancing provider adoption of patient-reported outcome measures (PROMs) through implementation science: insights from two international workshops. J Patient Rep Outcomes. 2025 Jul 1;9(1):77. doi: 10.1186/s41687-025-00911-3. PMID: 40591164; PMCID: PMC12214070.

While not PROMIS-specific, this article is a valuable look at applying implementation science principles to the uptake of patient-reported outcome measures, with a focus on provider adoption and the Capability, Opportunity, Motivation-Behavior (COM-B) model and the Theoretical Domains Framework.